Hi!
On Win 10 64 bit, I'm using Epic Orchestra 2.0 (1.1.1838 same happened with 1.1.1780): I can insert Syncron player in a track, load a patch (appassionata strings) and play for the whole day. Then, if I save the project, close it and reopen it, that's what happens: everything works until I try to play the track with Syncron Player, which crashes Cubase (it closes). If I remove the instance of Syncron Player before playing it via MIDI and reload a new instance, all good!
Thank you for helping, ciao!