I've got a MP 12 Core 3.46 with 64gigs ram and C8.5. I have my buffer set to 256 and use a setting of 2 buffers on the VEP instances. The pauses in audio are about hald a second which is somewhat tolorable.
I found that by running at 384 buffer cause ZERO dropouts with VEP...very interesting. However, the overall average CPU went up which was also weird. Changing the buffer in VEP to anything other than 2 would return the gap in audio.
I have also noticed that hosting Vienna Instruments inside Cubase is causing a massive increase in average load. I disabled the tracks and the meter droped quite a bit. I am not running any reverbs inside VI so not sure why it's doing this. Guess I'll only use them if I really need that instrument.
With all this mess I'm really tempted to jump back to LPX that I've used for years.
Chris
EDIT:
Will I did find a couple things that helped my situation. I did notice that Vienna Instruments AG2 settings were inactive so I re-enabled them and the load is much better. I also have gotten used to the brief pause.
I also had migrated from a quad core i7 Mini to the 12 core MP. I only recently realized I had not increased the CORE count in Kontakt or on the local VEP. On top of that the PC Slave I went from 4 to 8 cores and missed increasing that as well. Average ASIO load is much better.