Hi Daniel001,
I found out that editing of saved metaframes is very buggy.
Don't edit a (loaded) metaframe and save it. You risk to damage it. Only save completely new, reestablished metaframes. It means: if you want to create and save a metaframe...
1. create a blanc metaframe (File->Clear All),
2. add as many instances as you need,
3. fill this instances with your instruments (loading of saved projects is ok!)
4. save this metaframe.
If you reload this metaframe everything should be allright. But don't edit and save this metaframe again, in my case it often crashs after reloading (in combination with "Play")!!!!
With this rules I managed to get VE PRO and Play worked again.
Best regards,
Peter